A Phase II Study of Maintenance Therapy With Temsirolimus in Androgen-Independent Prostate Cancer After First Line Chemotherapy With Docetaxel
This is a clinical trial (a type of research study). You are being asked to consider taking part in this study because you have cancer of the prostate gland that no longer responds to hormonal treatment, and are receiving treatment with docetaxel and prednisone. The usual care is to continue the chemotherapy (docetaxel) until your cancer no longer responds to the treatment, or to have a break with re-treatment with chemotherapy when the cancer progresses. Eventually, prostate cancer no longer responds to docetaxel chemotherapy.
This research is being done to find out if temsirolimus given to patients after docetaxel and prednisone therapy can delay the progression of prostate cancer.
Eligible patients will receive temsirolimus at a dose of 25 mg IV every week until disease progression or unacceptable toxicity. One cycle consists of 4 weeks of therapy. At the time of treatment failure, further therapy (not with temsirolimus) is at the discretion of the treating physician.
Reviewed by OCREB
Print this page and take it to your doctor to discuss your eligibilty and treatment options. Only your doctor can refer you to a clinical trial.
These resources are provided in partnership with the
Canadian Cancer Society