Pilot Study to Evaluate Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumour Response to Neoadjuvant Chemotherapy Pilot Study to Evaluate Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumour Response to Neoadjuvant Chemotherapy

Official Title

Pilot Study to Evaluate Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumour Response to Neoadjuvant Chemotherapy

Summary:

Our objective in this pilot study will be to identify PA parameters that can distinguish benign vs. malignant lesions, and also, if PA parameters change with within breast tumours during chemotherapy treatment over time.

Trial Description

Primary Outcome:

  • Treatment response correlation between photoacoustic parameters and histopathological measurement.
Secondary Outcome:
  • Breast mass characterization
This study will investigate photoacoustic tissue characteristics of breast lesions both at diagnosis, and within a separate subgroup of patients, physiological changes in breast tumours during neoadjuvant chemotherapy (NAC). Our objective in this pilot study will be to identify PA parameters that can distinguish benign vs. malignant lesions, and also, if PA parameters change with within breast tumours during chemotherapy treatment over time. Our hope is to use this information to correlate with pathological response.

View this trial on ClinicalTrials.gov

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Resources

Canadian Cancer Society

These resources are provided in partnership with the Canadian Cancer Society