Phase III Randomized Controlled Trial and Economic Evaluation of Stereotactic Ablative Radiation Therapy for Comprehensive Treatment of Oligometastatic (1-3 Metastases) Cancer (SABR-COMET-3)
Stereotactic Ablative Radiation Therapy (SABR) is a modern RT technique that delivers high doses of radiation to small tumour targets using highly conformal techniques. SABR is non-invasive and delivered on an outpatient basis. The purpose of this study is to compare the effect of SABR, relative to standard of care (SOC) alone, on overall survival, progression-free survival, toxicity, and quality of life. An integrated economic evaluation will determine the cost per quality of life year gained using SABR (vs. SOC) and a translational component will enable identification of predictive/prognostic biomarkers of the oligometastatic state.
Primary Outcome:
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