18F-DOPA PET Imaging: an Evaluation of Biodistribution and Safety

Official Title

18F-DOPA PET Imaging: an Evaluation of Biodistribution and Safety

Summary:

Single centre prospective cohort phase III study of 18F-DOPA PET/CT imaging in specific patient populations:
1. Pediatric patients with congenital hyperinsulinism
2. Pediatric patients with neuroblastoma
3. Pediatric or Adult patients with suspected extra-pancreatic neuroendocrine tumour
4. Adult patients with a clinical suspicion of Parkinson's disease
5. Pediatric or Adult patients with primary brain tumours
This study will evaluate the biodistribution and safety of 18F-DOPA produced at the Edmonton PET Centre.

Trial Description

Primary Outcome:

• Immediate safety evaluation

• Delayed safety evaluation
• Delayed safety evaluation - referring physician
• Biodistribution: scan interpreter will evaluate the distribution of tracer and comment if expected
• Perceived clinical benefit

View this trial on ClinicalTrials.gov