Improving the Specificity of Breast MRI Through Diffusion Tensor Breast MRI (DTI)
The breast MRI is used in the preoperative scenario to evaluate the extension of a newly
diagnosed breast cancer and to screen the contralateral breast. The scan consists of a
series of images taken after the use of intravascular contrast media that may detect areas
of enhancement that look malignant, but are actually benign tissue, producing a false
positive result. The investigators aim to evaluate a novel MRI sequence of images that does
not use contrast, diffusion tensor imaging (DTI). Addition of DTI sequence does not add
significantly to the time of standard breast MRI exam. This novel technique provides
improved detection of tissue microstructure and is able to differentiate malignant from
benign tumour. Hence, the investigators hypothesize that DTI may decrease the false positive
rate when compared with standard dynamic contrast-enhanced (DCE) MRI.
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