The PRICE Trial: Phlebotomy Resulting in Controlled Hypovolemia to Prevent Blood Loss in Major Hepatic Resections
Major liver resection is associated with substantial intraoperative blood loss. Blood loss
in elective liver surgery is a significant factor of perioperative morbidity and mortality,
as well as possibly long-term oncologic outcome. The purpose of this study is to use whole
blood phlebotomy to decrease the central venous pressure, resulting in a state of relative
hypovolemia. It is hypothesized that this intervention will lead to a decrease in blood loss
at the time of liver resection.
View this trial on ClinicalTrials.gov
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