A Phase 2 Randomized, Double-blind, Window of Opportunity Trial Evaluating Clinical and Correlative Effects of Chloroquine as a Novel Therapeutic Strategy in Breast Cancer
Chloroquine (CQ) is a well known, well tolerated medication that has been used for many
years traditionally for arthritis, lupus, and malaria. It has anti-inflammatory properties
but is often the drug of choice for arthritis and malaria due to its few side effects.
Recently, laboratory investigations have proven that CQ may potentially have anti-cancer
properties, by inhibiting a process which allows cancers such as breast cancer to continue
to grow (a process known as "autophagy"). Therefore, this study will look at how well CQ can
inhibit the growth of breast cancers in patients while waiting for surgery.
View this trial on ClinicalTrials.gov
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