A Randomized Open-Label Phase III Trial of MK-3475 Versus Platinum Based Chemotherapy in 1L Subjects With PD-L1 Strong Metastatic Non-Small Cell Lung Cancer
This is an efficacy and safety study to assess pembrolizumab (MK-3475/SCH 900475) compared
to standard of care (SOC) platinum-based chemotherapies in the treatment of participants
with previously untreated stage IV, programmed cell death ligand 1 (PD-L1) strong expressing
Non-Small Cell Lung Cancer (NSCLC). The primary hypothesis of this study is that
participants with PD-L1 strong NSCLC will have a longer Progression Free Survival (PFS), as
assessed by Response Evaluation Criteria in Solid Tumours version 1.1 (RECIST 1.1) when
treated with pembrolizumab than when treated with platinum-based chemotherapies.
View this trial on ClinicalTrials.gov
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