The Epidemiology, Process and Outcomes of Spine Oncology (EPOSO)

Official Title

The Epidemiology, Process and Outcomes of Spine Oncology


The main purpose of this study is to utilize a comprehensive, prospective clinical database to collect patient, diagnostic and treatment variables along with disease specific and generic health related quality of life (HRQOL) data on consecutively treated patients with metastatic spine tumours. The objectives are to determine the validity and reliability of the Spine Cancer Outcomes Questionnaire (SCOQ) for use in the assessment of spine tumour outcomes, to determine if the Spine Instability Neoplastic Score (SINS) Classification is a valid tool for predicting the stability of spine in metastatic spine disease, and to determine the efficacy of surgery versus radiation therapy for the treatment of impending instability secondary to metastatic disease of the spine.

Trial Description

Primary Outcome:

  • Change in Spine Cancer Outcomes Questionnaire (SCOQ)
Secondary Outcome:
  • Change in Pain Numeric Rating Scale (NRS)
  • Change in EuroQoL 5D (EQ-5D)
  • Change in Short Form 36 version 2 (SF-36 v2)
  • Change in International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)

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Canadian Cancer Society

These resources are provided in partnership with the Canadian Cancer Society