A Multicentre Randomized Controlled Clinical Trial for the Reduction of Acute Skin Reaction in Adjuvant Breast Radiation in Large Breasted Women Using a Prone Technique - The Prone Breast Trial
Participants undergoing radiation after breast conserving surgery for an early breast cancer
(either Ductal Carcinoma In Situ (DCIS), or Early Stage Invasive breast cancer), and are at
increased risk of developing a skin reaction because of their large breast size.
After breast conserving surgery (also known as a 'lumpectomy'), women with either DCIS or
early stage invasive breast cancer receive radiation to the breast to decrease the risk of
cancer recurrence. Breast radiation is usually done with women lying on their back
("supine"). Some women develop temporary breakdown of the skin (moist desquamation). This
skin reaction can be painful and has been linked to long term side effects such as chronic
pain and decreased quality of life.
This study is being done because women with large breasts have higher rates of skin
breakdown (called 'moist desquamation') and breast pain during and shortly after radiation
therapy is complete. It is unclear if such skin reactions and pain would be improved by
alternating treatment position - namely lying on your belly ("prone") during their radiation
View this trial on ClinicalTrials.gov
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