Thermal Ablation With a Loosely Wound Helical Coil for Radiofrequency Treatment of Large Renal and Hepatic Tumours in Patients Undergoing Partial or Total Nephrectomy or Heptectomy
This is a clinical research study designed to determine the safety and efficacy of the
application of a unique interstitial radio frequency thermal therapy for the treatment of
large tumours in the kidney or liver. The novel device offers patients a more effective
therapy than conventional RFA and for patients with large tumours fewer number of treatments
and needle insertion sites. The clinical treatment volumes (or sites of focal tumours) will
be determined by a combination of biopsy and contrast enhanced CT imaging.
The study will assess if novel device can produce lesions in the liver or kidney in a
controlled and predictable manner and with sufficient size to effectively manage disease
progression in the organ. The extent of lesion size at a delivered power setting and
treatment time will be measured with post-treatment CT or MRI and biopsy as measures of
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