Evaluation of Polarized Reflectance Spectroscopy for Detection of High-risk Oral Lesions
In this study the investigators are conducting research to determine whether a new optical
device using polarization reflectance spectroscopy can help doctors or dentists identify
abnormalities in the mouth that require follow-up. To establish this, measurements are
needed from a large number of individuals with different abnormalities in their mouth.
The investigators believe the proposed approach has potential to improve and enable mass
screening for precancerous and early cancers of the oral cavity by improving the predictive
value of oral cavity exams, particularly for less experienced practitioners.
The information from this study will be compared to results from the pathology report of the
tissue taken from your mouth.
1. Polarized reflectance spectroscopy can distinguish high-risk oral lesion from normal
and reactive oral lesions.
2. Polarized reflectance spectroscopy can capture low-grade oral lesions that have
characteristics associated with a high risk of progression to cancer.
View this trial on ClinicalTrials.gov
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