Feasibility of a Prospective, Randomized Trial Comparing Surgery Versus Radiosurgery for the Treatment of Single Brain Metastases
Usually the treatment of a single brain metastasis is surgery or Stereotactic Radiosurgery
(SRS). Surgery involves resection of the brain tumour by means of an operation, whereas SRS
is treatment consisting of highly focused radiation doses to the tumour. These two treatment
modalities are both widely used, well established, and proven to improve survival, but so
far, no study has been done to directly compare the efficacy of one over the other. Neither
treatment in itself is considered to be experimental and both have been shown to provide
benefits to patients with metastatic brain tumours. The aim of this study is to determine
which two modalities are better for local control and improving quality of life.
Patients who consent to this study will be randomized to either receive surgery or
Radiosurgery in the treatment of single brain metastases. The study seeks to recruit 12
patient to each group. Patients will be in this study for up to five years from the time of
the treatment finished. This will include follow-up visits at 4 weeks after the procedure
and then every 3 months after the procedure up to 5 years.
View this trial on ClinicalTrials.gov
Print this page and take it to your doctor to discuss your eligibilty and treatment options. Only your doctor can refer you to a clinical trial.
These resources are provided in partnership with the
Canadian Cancer Society