Phase I Parallel Arm Study of MK-0646 (Dalotuzumab) + MK-2206 and MK-0646 (Dalotuzumab) + MK-0752 Doublets (MK-MK Doublets) in Patients With Advanced Cancer
This is an open-label, two-part study to evaluate the safety and tolerability of combination treatment with dalotuzumab + MK-2206 or dalotuzumab + MK-0752. Preliminary anti-tumor activity of these combinations in groups of participants with specific types of cancer will be assessed. The study will determine the dose limiting toxicities (DLTs) observed after administration of each of the combinations at various doses and define the maximum tolerated dose of each combination.
Primary Outcome:
View this trial on ClinicalTrials.gov
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