Steroid Induced Osteoporosis in the Pediatric Population Ancillary Study- Osteonecrosis in Children With Acute Lymphoblastic Leukemia
Acute lymphoblastic leukemia is the most common form of childhood cancer with current
treatment survival rates approaching 80%. Improved outcomes show an increased number of
survivors at risk for long-term treatment related side effects including osteonecrosis.
Osteonecrosis, or bone death, is caused by blood supply loss to the bone causing pain and
poor quality of life. The hips, shoulders, knees and ankles may be affected. Pain is the
usual presenting symptom and may become severe requiring surgical decompression or
replacement of the affected joint. Long-term effects including arthritis and progressive
joint difficulties will not be known for decades. This study aims to determine the risk
factors for developing osteonecrosis that will lead to information for earlier detection and
prevention. The study will be the basis for future intervention and prevention trials.
View this trial on ClinicalTrials.gov
Print this page and take it to your doctor to discuss your eligibilty and treatment options. Only your doctor can refer you to a clinical trial.
These resources are provided in partnership with the
Canadian Cancer Society